PRP Tubes with ACD Gel and Sodium Citrate: Premium Dual Anticoagulant Technology for Superior PRP Quality

Our PRP Tubes with ACD Gel and Sodium Citrate represent advanced platelet-rich plasma collection technology, combining the complementary benefits of dual anticoagulants with precision gel separation for consistently superior PRP preparation. Designed for medical professionals who demand the highest quality platelet concentrations and growth factor preservation, these premium tubes deliver clinical-grade results for aesthetic treatments, hair restoration procedures, orthopaedic therapies, and regenerative medicine applications across all specialties.

The Science of Dual Anticoagulation

Unlike basic single-anticoagulant tubes, our advanced dual-system combines ACD (Acid Citrate Dextrose) and Sodium Citrate for synergistic platelet protection. This sophisticated formulation provides superior platelet viability preservation compared to single agents, enhanced growth factor integrity during processing, prevention of premature platelet activation before therapeutic use, extended platelet survival during preparation windows, and more consistent results across diverse patient populations.

The dual anticoagulant approach addresses multiple coagulation pathways simultaneously, creating optimal conditions for platelet preservation that single-agent systems simply cannot match.

ACD Component: Gold Standard Platelet Preservation

The Acid Citrate Dextrose (ACD) portion provides critical advantages for therapeutic PRP preparation. ACD maintains optimal pH levels supporting platelet metabolism, the dextrose component provides energy substrate for platelet survival, the acid-citrate buffer stabilises blood chemistry preserving cellular function, and it has established superiority in applications requiring maximum platelet viability.

ACD is the gold standard anticoagulant in transfusion medicine and regenerative therapies, chosen specifically for its exceptional platelet preservation properties.

Sodium Citrate Component: Calcium Chelation Excellence

Sodium Citrate contributes complementary protective mechanisms through powerful calcium chelation. By binding free calcium ions, Sodium Citrate prevents calcium-dependent coagulation cascade initiation, blocks premature platelet activation that depletes growth factors, maintains platelets in resting state until intentional activation, and provides fully reversible anticoagulation (adding calcium activates platelets precisely when desired).

This reversible calcium chelation is particularly valuable for PRP applications where controlled platelet activation at treatment time maximises therapeutic benefit.

Synergistic Protection: Why Dual Systems Excel

The combined ACD and Sodium Citrate formulation creates synergistic advantages exceeding either component independently. The dual system offers broader protection against multiple coagulation pathways, more effective maintenance of platelet resting state, superior growth factor potency preservation, processing flexibility across various centrifugation protocols, and more consistent high-quality results regardless of patient variables.

This comprehensive anticoagulation translates directly to superior clinical outcomes in regenerative medicine applications.

Thixotropic Gel Separator Technology

The integrated gel separator is crucial for efficient, clean PRP preparation. During centrifugation, this specialized thixotropic gel migrates based on density to form a stable physical barrier between red blood cells and plasma layers. The gel separation provides clear visual demarcation for precise PRP extraction, prevents red blood cell contamination of plasma, facilitates clean platelet harvest without mixing, and simplifies the collection procedure for consistent results.

The gel's specific density is precisely calibrated for optimal PRP protocols, positioning itself exactly where needed to maximise platelet-rich plasma yield while excluding unwanted cellular components.

Superior Growth Factor Preservation

Platelets contain numerous growth factors essential for PRP's regenerative effects including Platelet-Derived Growth Factor (PDGF) promoting cellular proliferation, Transforming Growth Factor-beta (TGF-β) regulating inflammation and healing, Vascular Endothelial Growth Factor (VEGF) stimulating angiogenesis, Epidermal Growth Factor (EGF) promoting epithelial regeneration, Insulin-like Growth Factor (IGF) supporting tissue repair, and Fibroblast Growth Factor (FGF) facilitating wound healing.

The dual anticoagulant formulation protects these biological mediators from degradation during collection and processing, ensuring maximum growth factor availability when PRP is administered therapeutically. Preserved growth factor potency directly correlates with treatment effectiveness and patient outcomes.

Comprehensive Clinical Applications

PRP Tubes with ACD Gel and Sodium Citrate support the full spectrum of platelet-rich plasma therapies:

Aesthetic and Cosmetic Medicine: Facial rejuvenation and natural skin tightening, reduction of fine lines and wrinkles, improvement of skin texture and radiance, treatment of acne scars and hyperpigmentation, under-eye dark circle and hollowing correction, neck and décolletage rejuvenation, hand rejuvenation treatments, overall facial volume enhancement through collagen stimulation, and microneedling enhancement with PRP.

Hair Restoration and Trichology: Andro genetic alopecia treatment in men and women, hair density and thickness improvement, stimulation and regeneration of dormant hair follicles, post-hair transplant healing and graft survival enhancement, treatment of various pattern hair loss conditions, eyebrow and beard hair restoration, alopecia aerate management, and overall scalp health optimisation.

Orthopaedic and Sports Medicine: Tendon injury healing (rotator cuff, Achilles, patellar, tennis elbow), ligament sprain and tear recovery support, osteoarthritis pain relief and cartilage protection, meniscus tear healing facilitation, chronic joint pain management, plantar fasciitis treatment, sports injury recovery acceleration, and post-surgical orthopaedic healing enhancement.

Additional Regenerative Applications: Chronic wound healing acceleration, diabetic ulcer treatment, post-surgical recovery enhancement, dental bone regeneration for implants, periodontal tissue healing, scar revision and improvement, TMJ disorder management, and various tissue regeneration protocols.

Simple 4-Step Preparation Protocol

Using our ACD Gel and Sodium Citrate PRP tubes follows a straightforward clinical workflow:

Step 1: Blood Collection Draw patient blood directly into the PRP tube via standard venipuncture technique. The vacuum seal automatically draws the correct blood volume ensuring proper anticoagulant ratio.

Step 2: Gentle Mixing Immediately and gently invert the tube 8-10 times to thoroughly mix blood with anticoagulants. Avoid vigorous shaking that could damage platelets—gentle inversions ensure complete mixing without cellular trauma.

Step 3: Centrifugation Process within 2-4 hours for optimal platelet viability. Centrifuge according to validated protocols specific to desired PRP concentration (typically 1500-3000 rpm for 5-15 minutes depending on centrifuge type and target platelet levels).

Step 4: PRP Extraction Carefully extract the platelet-rich plasma layer positioned above the gel separator barrier using sterile technique. Avoid disturbing the gel or drawing from the red blood cell layer below. Your pure, concentrated PRP is ready for activation (if desired) and therapeutic injection.

Complete centrifugation parameters and extraction techniques provided with every order to ensure optimal results.

Centrifugation Flexibility and Optimisation

The balanced dual anticoagulation system supports various centrifugation protocols, allowing practitioners to customise preparation based on specific treatment needs. Lower speed/shorter time protocols (e.g., 1500 rpm × 5 minutes) produce moderate platelet concentrations (3-4x baseline) suitable for certain aesthetic applications emphasising growth factors. Higher speed/longer time protocols (e.g., 2500-3000 rpm × 10-15 minutes) achieve maximum concentrations (5-7x baseline) preferred for orthopedic applications requiring dense platelet populations.

The tube performs consistently across this parameter range, unlike some systems optimised for only narrow processing windows. This flexibility allows protocol customisation for different clinical applications and patient needs.

Expected Platelet Concentration and Quality

Quality dual-anticoagulant PRP tubes with gel separation consistently achieve therapeutic platelet concentrations of 3-7x baseline levels depending on centrifugation protocol, patient baseline platelet counts, and extraction technique precision. This translates to 300,000-700,000+ platelets per micro liter in concentrated PRP—well within therapeutic ranges established for regenerative applications across specialties.

Beyond concentration, platelet quality matters critically. The dual anticoagulant system maintains platelet viability, functionality, and growth factor content superior to single-agent alternatives, translating to more robust clinical responses and improved patient outcomes.

Sterility and Patient Safety Standards

Each PRP tube undergoes rigorous quality control ensuring absolute sterility and safety. Manufacturing occurs in ISO-certified cleanroom environments, gamma sterilization or equivalent validated processes eliminate all microbial contamination, vacuum-seal integrity testing ensures consistent performance, medical-grade materials prevent any leaching or contamination, and batch testing validates sterility, anticoagulant concentration, and gel performance.

Since prepared PRP will be re-injected into patients, absolute sterility throughout collection and preparation is non-negotiable. Our tube design supports sterile protocols at every step from initial blood draw through final PRP extraction.

Professional Medical Use - Training Recommended

PRP tubes with ACD Gel and Sodium Citrate are medical devices intended exclusively for qualified healthcare professionals including dermatologists and aesthetic medicine physicians, plastic and cosmetic surgeons, orthopaedic surgeons and sports medicine specialists, physiatrists and rehabilitation physicians, trichologists and hair restoration doctors, trained medical aesthetic practitioners under physician supervision, and dentists performing regenerative procedures.

Proper training in phlebotomy technique, sterile procedure protocols, centrifugation optimisation, PRP extraction methods, and injection techniques is essential for safe, effective treatments delivering optimal patient outcomes.